SERUM LEVELS OF OXIDATIVE STRESS MARKERS IN SUBCLINICAL AND OVERT HYPOTHYROIDISM VERSUS CONTROL GROUP IN POPULATION OF KUTAHYA CITY, TURKEY

Yontem M., Arslan S., Erdogdu B. S., KOÇAK F. E.

GOMAL JOURNAL OF MEDICAL SCIENCES, vol.19, no.4, pp.132-140, 2021 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 4
  • Publication Date: 2021
  • Doi Number: 10.46903/gjms/19.04.935
  • Journal Name: GOMAL JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.132-140
  • Keywords: Hypothyroidism, Thyroid Stimulating Hormone, Oxidants, Antioxidants, Oxidative Stress, Paraoxonase-1, Total Oxidant Status, Total Antioxidant Status, Oxidative Stress Index, Arylesterase, PARAOXONASE ARYLESTERASE, ANTIOXIDANT STATUS, LDL
  • Kütahya Health Sciences University Affiliated: Yes

Abstract

Background: Overproduction of oxygen-related free radicals and inadequate antioxidant defense are critical in hypothyroidism, as they might lead to future life-threatening diseases. The objectives of this study were to compare serum levels of oxidative stress markers; total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase-1 (PON-1), and arylesterase (ARYL) in patients with subclinical hypothyroidism (SH) and overt hypothyroidism (OH) versus healthy controls in population of Kutahya city, Turkey.