SERUM LEVELS OF OXIDATIVE STRESS MARKERS IN SUBCLINICAL AND OVERT HYPOTHYROIDISM VERSUS CONTROL GROUP IN POPULATION OF KUTAHYA CITY, TURKEY
GOMAL JOURNAL OF MEDICAL SCIENCES, cilt.19, sa.4, ss.132-140, 2021 (ESCI, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.46903/gjms/19.04.935
- Dergi Adı: GOMAL JOURNAL OF MEDICAL SCIENCES
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
- Sayfa Sayıları: ss.132-140
- Anahtar Kelimeler: Hypothyroidism, Thyroid Stimulating Hormone, Oxidants, Antioxidants, Oxidative Stress, Paraoxonase-1, Total Oxidant Status, Total Antioxidant Status, Oxidative Stress Index, Arylesterase, PARAOXONASE ARYLESTERASE, ANTIOXIDANT STATUS, LDL
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Overproduction of oxygen-related free radicals and inadequate antioxidant defense are critical in hypothyroidism, as they might lead to future life-threatening diseases. The objectives of this study were to compare serum levels of oxidative stress markers; total oxidant status (TOS), total antioxidant status (TAS), oxidative stress index (OSI), paraoxonase-1 (PON-1), and arylesterase (ARYL) in patients with subclinical hypothyroidism (SH) and overt hypothyroidism (OH) versus healthy controls in population of Kutahya city, Turkey.