Research Information System
Osteoporoz Dünyasından Dergisi, vol.15, pp.11-15, 2009 (Peer-Reviewed Journal)
Aim: Osteoporotic vertebral fractures and increased kyphotic angle may cause disturbances in pulmonary functions. Our aim was to evaluate pulmonary function and quality of life in osteoporotic patients.
Material and Methods: Fifty-one patients with osteoporosis and 19 osteopenic subject, followed in our outpatient clinic, we- re included. Their demographics were recorded. All the subjects were submitted to pulmonary function test (PFT) and dorsal lateral radiography was obtained to measure Cobb angle. Global body pain was assessed using Visual Analogue Scale (VAS) and quality of life was assessed using Short Form-36 (SF-36) questionnaire.
Results: The mean ages were 63.3±8.7 in osteoporosis and 55.3±7.3 in osteopenia groups (p=0.001). Body mass index of the osteoporosis group was significantly lower than osteopenia group (28.8±5.7 and 32.2±5.5, respectively, p=0.029). In osteopo- rosis group compared to osteopenia group, the absolute forced expiratory volume in 1 second (FEV1) (1.8±0.4 and 2.1±0.5, respectively, p=0.018) and absolute forced vital capacity (FVC) (2.2±0.5 and 2.6±0.6, respectively, p=0.005) were significantly lower. No differences were found between two groups concerning other PFT parameters. The mean Cobb angle was higher in osteoporosis group than osteopenia group, but the difference was not significant (32.7±12.4 and 28.5±9.5, respectively, p=0.194). When all the subjects were considered, no correlation was found between Cobb angle and PFT parameters (p>0.05). No significant difference was found between two groups in respect to VAS and SF-36 scores (p>0.05). Conclusion: We found absolute FEV1 and absolute FVC significantly lower in osteoporosis group compared to osteopenia group. But we observed no differences in % predicted FEV1 and % predicted FVC. We supposed that the differences we- re because the subjects in osteopenia group were younger and fatter. The pulmonary functions and quality of life of the osteoporotic patients with a kyphotic angle up to studied are not worse than the osteopenic people. (From the World of Osteoporosis 2009;15:11-5)
Key words: Osteoporosis, kyphosis, pulmonary function, quality of life
Amaç: Osteoporoza ba¤l› vertebral k›r›klar ve kifoz aç›s›nda art›fla ba¤l› solunum fonksiyonlar›nda bozulmalar olabilir. Amac›m›z osteoporozu olan hastalar›n solunum fonksiyonlar›n› ve yaflam kalitelerini de¤erlendirmektir.
Gereç ve Yöntem: Çal›flmam›za poliklini¤imizde takip edilen 51 osteoporoz (49 kad›n, 2 erkek) ve 19 osteopenik kifli (18 kad›n, 1 er- kek) al›nd›. Kat›l›mc›lar›n demografik özellikleri kaydedildi, solunum fonksiyon testi (SFT) yap›ld› ve dorsal lateral grafileri çekilerek Cobb aç›s› ölçüldü. Genel vücut a¤r›s› Vizüel Analog Skala (VAS) ile, yaflam kalitesi Short Form-36 (SF-36) anketi ile de¤erlendirildi. Bulgular: Yafl ortalamas› osteoporoz grubunda 63,3±8,7, osteopeni grubunda 55,3±7,3 y›l idi (p=0,001). Osteoporoz grubunun vü- cut kitle indeksi, osteopeni grubuna göre anlaml› olarak daha düflüktü (s›ras›yla 28,8±5,7, 32,2±5,5, p=0,029). Osteoporoz grubun- da osteopeni grubuna göre ölçülen birinci saniyedeki zorlu ekspirasyon volümü (FEV1) (s›ras›yla 1,8±0,4, 2,1±0,5, p=0,018) ve ölçü- len zorlu vital kapasite (FVC) (s›ras›yla 2,2±0,5, 2,6±0,6, p=0,005) de¤erleri anlaml› olarak daha düflük bulundu. ‹ki grup aras›nda di- ¤er SFT parametreleri aç›s›ndan anlaml› farkl›l›k saptanmad›. Ortalama Cobb aç›s› osteoporoz grubunda osteopeni grubuna göre daha yüksekti, ancak aralar›ndaki farkl›l›k istatistiksel anlaml› bulunmad› (s›ras›yla 32,7±12,4, 28,5±9,5, p=0,194). Tüm hastalar de- ¤erlendirildi¤inde Cobb aç›s› ile SFT parametreleri aras›nda anlaml› korelasyon saptanmad› (p>0,05). Her iki grubun VAS ve SF-36 anketi skorlar› aras›nda anlaml› farkl›l›k saptanmad› (p>0,05).
Sonuç: Osteoporoz grubunda osteopeni grubuna göre solunum fonksiyonlar›ndan ölçülen FEV1 ve ölçülen FVC de¤erlerini anlam- l› olarak daha düflük bulduk. Ancak %FEV1 ve %FVC de¤erleri aras›nda anlaml› farkl›l›k saptamad›k. Osteopeni grubunun daha genç ve daha kilolu olmas›ndan dolay› ölçülen de¤erlerdeki farkl›l›klar›n olufltu¤unu düflündük. Kifoz aç›s› ortalamas› çal›flmam›z- daki kadar olan osteoporoz hastalar›n›n solunum fonksiyonlar› ve yaflam kaliteleri osteopenik kiflilerden daha kötü de¤ildir. (Osteoporoz Dünyas›ndan 2009;15:11-5)
Anahtar kelimeler: Osteoporoz, kifoz, pulmoner fonksiyon, yaflam kalitesi