Overview of hematopoietic stem cell transplantation
Journal of Experimental and Clinical Medicine (Turkey), cilt.40, sa.1, ss.127-131, 2023 (Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 40 Sayı: 1
- Basım Tarihi: 2023
- Doi Numarası: 10.52142/omujecm.40.1.27
- Dergi Adı: Journal of Experimental and Clinical Medicine (Turkey)
- Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, EMBASE
- Sayfa Sayıları: ss.127-131
- Anahtar Kelimeler: graft versus host disease (GVHD), hematopoietic stem cell transplantation (HSCT), human leukocyte antigen (HLA), stem cell (SC)
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Kütahya Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Hematopoietic stem cell transplantation (HSCT) is the intravenous administration of hematopoietic stem cells (HSC) to restore blood cell production in individuals whose bone marrow or immune system is damaged or dysfunctional. This approach has been used to treat various malignant and nonmalignant disorders for the past half-century. HSCT is performed in two ways, autologous and allogeneic. In the clinic, the type of stem cell transplant is decided according to the patient's diagnosis. Both kinds of transplantation have advantages as well as disadvantages. Knowing and managing the HSCT process well affects the success of the transplant. Knowing the complications that may occur after transplantation will facilitate the patient’s treatment process. In this short review, the HSCT process has been tried to be explained with general titles.